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LYFSTONE®

CALPROTECTIN

Be Sure Faster – Innovation in PJI Diagnostics

Lyfstone® Calprotectin – an innovative bedside rapid test to rule-out prosthetic joint infection (PJI) from the patient’s synovial fluid in only 15 minutes. A professional solution for healthcare professionals to provide a precise diagnosis and make the right decision faster and more efficiently.

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screen of phone with Lyfstone app on it

Periprosthetic Joint Infections

Periprosthetic Joint Infection (PJI) is one of the greatest challenges in orthopaedics. PJI can lead to emotional, financial and physical trauma for patients. A fast and accurate diagnosis of PJI is vital to making the right treatment decisions.

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A NEW ADVANCEMENT
IN DIAGNOSING PJI

In a prosthetic joint, the first priority is to reliably rule out infection. The Lyfstone® test is a CE-IVD labelled Point of Care test, which measures the amount of Calprotectin in Synovial Fluid. Calprotectin is abundantly present in neutrophils. The presence of neutrophils is a hallmark of PJI, and a massive release of calprotectin occurs upon encounter with pathogens. Elevated levels of calprotectin are proven indicators of both acute and chronic PJI.
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clear and reliable risk indicators

The lateral flow rapid test is combined with the Lyfstone® app to give an exact quantitative measurement of the level of calprotectin in Synovial fluid. Just hold the smartphone above the sample and align the screen layout with the support frame. The calprotectin concentration and the risk stratification group of the sample are displayed on the screen.
  • LOW risk of infection
  • MODERATE risk of infection
  • HIGH risk of infection
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CLINIC­ALLY PROVEN

In a prospective clinical study of 123 patients at a leading US Hospital using the MSIS-13 criteria as comparator, the Lyfstone® Calprotectin test showed excellent sensitivity (98.1%) and specificity (95.7%). The calprotectin test outperformed blood-based PJI diagnostic tests such as CRP and ESR, confirming its diagnostic utility.


Source:
Diagnostic Utility of a Novel Point-of-Care Test of Calprotectin for Periprosthetic Joint Infection after Total Knee Arthroplasty
A Prospective Cohort Study.

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why lyfstone® calprotectin?

Improving
quality of life

Lyfstone® enables the early identification of periprosthetic joint infection, which can prevent later complications or further surgeries.

TIME SAVING

The surgeon can extract the synovial fluid and perform the test immediately while the patient is still present

COST SAVING

Faster PJI diagnosis results in less bed-days for the patient.

Be sure.
faster.

To assess the risk of periprosthetic joint infection, a small amount of synovial fluid is extracted from the patient’s joint. The Lyfstone® test requires only 20 μl and generates results in 15 minutes. The easy sample work-up allows implementation at any stage of care, from consulting to pre-op to per-op.
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Get in touch with

our distributors Or contact Lyfstone directly on info@lyfstone.com

in europe

Our professional distributors
are available throughout Europe. Choose the one closest to you and contact your sales representative today.
Find your Distributor

Get in touch with

our distributors Or contact Lyfstone directly on sales@lyfstone.com

in europe

Our professional distributors
are available throughout Europe. Choose the one closest to you and contact your sales representative today.

Find your Distributor

Find our latest published studies here!

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